Post-doc available

The Hawkins group has a BBSRC funded post-doc available for 2023-6.

We are looking for a highly motivated Research Associate to work on a BBSRC-funded project aimed at characterising collisions of the bacterial replication machinery with protein obstacles. This project will exploit the biochemical tractability of Escherichia coli to investigate fundamental aspects of DNA replication at the DNA, protein and complex/super-complex level. The project will focus on studying the mechanistic consequences of replication obstacles for replisomes, resolution of replisome collisions by helicases, and understanding the impact of replication-transcription conflicts on genome duplication. Developing a full molecular understanding of replisome-obstacle collisions is currently a major challenge in the field because they can impede replication fork progression and cause genome instability.

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AKTA Go!

A new AKTA machine has been set up in our lab. This will open up more opportunities for future protein purification.

UK DNA Replication Meeting

In September 2022 Dom attended the first UK DNA Replication meeting and presented her first conference poster.

This three day conference organised by the biochemical society and hosted at Birmingham University was an amazing opportunity to learn about the most recent findings in the field and to meet new collaborators.

During the second day, I was able to present a poster illustrating my ongoing PhD work. It was a great chance to receive feedback and advice from experts in the field.

It was an amazing conference.